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Radiation Dose Prediction for Cervical Cancer Patients Using IMRT Technique with a Machine Learning Model Based on Support Vector Regression (SVR)


 
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1. Title Title of document Radiation Dose Prediction for Cervical Cancer Patients Using IMRT Technique with a Machine Learning Model Based on Support Vector Regression (SVR)
 
2. Creator Author's name, affiliation, country R. F. Mushaddaq; University of Indonesia, Jl. Lingkar, Pondok Cina, Beji, Depok City, West Java, 16424, Indonesia
 
2. Creator Author's name, affiliation, country D. S. K. Sihono; University of Indonesia, Jl. Lingkar, Pondok Cina, Beji, Depok City, West Java, 16424, Indonesia; Indonesia
 
2. Creator Author's name, affiliation, country P. Prajitno; University of Indonesia, Jl. Lingkar, Pondok Cina, Beji, Depok City, West Java, 16424, Indonesia; Indonesia
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Cervical cancer; Support Vector Regression (SVR); Radiotherapy planning; Machine learning; Intensity Modulated Radiation Therapy (IMRT)
 
4. Description Abstract Cervical cancer poses significant global health challenges, necessitating the need for innovative treatment approaches. This study addresses the gap in current radiotherapy methods by integrating Support Vector Regression (SVR) to predict radiation doses for cervical cancer treatment, thereby enhancing the precision of Intensity Modulated Radiation Therapy (IMRT). Using datasets from 102 and 173 cervical cancer cases, we developed and validated an SVR model to predict dose distributions based on radiomic and dosiomic features. The model demonstrated strong performance, achieving a Mean Absolute Error (MAE) of 0.069 for the testing data, with specific performance metrics as follows: bladder mean dose MAE of 0.0693, bowel mean dose MAE of 0.0926, and rectum mean dose MAE of 0.0779. These findings highlight the potential of machine learning to refine radiotherapy planning, reduce the workload on medical physicists, and improve patient outcomes. Future research should focus on expanding dataset sizes and enhancing model precision, particularly for anatomically challenging regions.
 
5. Publisher Organizing agency, location National Research and Innovation Agency
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 2024-11-25
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://atomindonesia.brin.go.id/index.php/aij/article/view/1483
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.55981/aij.2024.1483
 
11. Source Title; vol., no. (year) Atom Indonesia; Vol 50, No 3 (2024): DECEMBER 2024
 
12. Language English=en en
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2024 Atom Indonesia
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